Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Malaria
Research from New York University, Medical Department has provided new information about malaria
May 28th, 2008
"The irradiated-sporozoite vaccine elicits sterile immunity against Plasmodium parasites in experimental rodent hosts and human volunteers. Based on rodent malaria models, it has been proposed that CD8(+) T cells are the key protective effector mechanism required in sporozoite-induced immunity," researchers in the United States report. "To investigate the role of class II-restricted immunity in protective immunity, we immunized beta(2)-microglobulin knockout (beta M-2(-/-)) Mice with irradiated Plasmodium yoelii or P. berghei sporozoites. Sterile immunity was obtained in the CD8(+)-T-cell-deficient mice immunized with either P. berghei or P. yoelii sporozoites. beta...
Source: Vaccine Weekly (2008-05-28)
|
