Vaccines
Reports outline vaccines study results from University of Sao Paulo
Published in Vaccine Weekly, May 28th, 2008
Fresh data on vaccines are presented in the report 'Use of proteoliposome as a vaccine against Trypanosoma cruzi in mice.' "We have generated proteoliposomes carrying proteins of Trypanosoma cruzi for use as immunogens in BALB/c mice. T. cruzi trypomastigote and amastigote forms were sonicated and mixed with SDS, with 94% recovery of soluble proteins. To prepare proteoliposomes, we have used a protocol in which dipalmitoylphosphatidylcholine, dipalmitoyl-phosphatidylserine and cholesterol were incubated with the parasite proteins," scientists writing in the journal Chemistry and Physics of Lipids report.
"BALB/c mice immunized with 20microg were...
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Source: Vaccine Weekly (2008-05-28)
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