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Newcastle Disease
Studies from Q. Gao et al add new findings in the area of Newcastle disease
June 4th, 2008
"Paramyxoviruses belong to the Paramyxoviridae family of the order Mononegavirales. They have a nonsegmented negative-stranded RNA genome and can cause a number of diseases in humans and animals," scientists in the United States report. "We generated a recombinant Newcastle disease virus (NDV) possessing a two-segmented genome. Each genomic segment is flanked by authentic NDV 3 ' and 5 ' noncoding termini allowing for efficient replication and transcription. A reporter gene encoding green fluorescent protein (GFP) was inserted into one segment, and a red fluorescent protein dsRed gene was inserted into the other segment in order to easily detect the replication and...
Source: Vaccine Weekly (2008-06-04)
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