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Vaccine Weekly

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Corneal Neovascularization Vaccines



Research on corneal neovascularization vaccines reported by scientists at Keio University, Department of Ophthalmology



June 4th, 2008

Current study results from the report, 'Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2,' have been published. In this recent report published in the journal Investigative Ophthalmology & Visual Science, researchers in Tokyo, Japan conducted a study "To investigate whether the induction of cytotoxic T lymphocytes (CTLs) targeting VEGF receptor 2 inhibits corneal neovascularization caused by alkali injury. H-2Db-restricted peptide corresponding to amino acids 400 to 408 of VEGF receptor 2 (VEGFR2(400-408)) was used as an epitope peptide."

"Dendritic cells (DCs) were harvested from bone marrow...


Source: Vaccine Weekly (2008-06-04)

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