Atherosclerosis

Malmo University publishes research in atherosclerosis

Published in Vaccine Weekly, June 4th, 2008

"Atherosclerosis is a chronic inflammatory disease characterized by accumulation of oxidized lipoproteins, increased cell death and hypertrophic degeneration of the arterial intima. The disease process is associated with local formation of modified self antigens that are targeted by both innate and adaptive immune responses," scientists writing in the Journal of Internal Medicine report.

"Although it remains to be firmly established it is likely that these autoimmune responses initially have a beneficial effect facilitating the removal of potentially harmful rest products from oxidized LDL and dying cells. However, studies performed on hypercholesterolaemic mice...

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Source: Vaccine Weekly (2008-06-04)

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