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Vaccine Weekly

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Cancer Vaccines



Researchers from University of Minnesota discuss findings in cancer vaccines



June 4th, 2008

In this recent report published in the American Journal of Clinical Oncology - Cancer Clinical Trials, researchers in the United States conducted a study "To evaluate the safety and activity of large multivalent immunogen (LMI), prepared by immobilizing autologous tumor cell plasma membrane on 5-mu m diameter silica beads, in patients with melanoma and renal cell carcinoma (RCC). Thirty patients with stage IV metastatic melanoma and 31 patients with stage IV RCC were randomly assigned to I of 3 trial arms and received monthly treatment with (1) LMI alone, (2) cyclophosphamide followed 8 days later with LMI, or (3) the same treatment as in arm 2 with IL-2 given for 5 days beginning 1...


Source: Vaccine Weekly (2008-06-04)

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