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Pleuropneumonia
Researchers from University of Nottingham publish new studies and findings in the area of pleuropneumonia
June 4th, 2008
According to a study from Nottingham, the United Kingdom, "Actinobacillus pleuropneumoniae is an important respiratory pathogen of swine, for which there is no highly effective vaccine. A phage expression library of the A. pleuropneumoniae genome was constructed and screened to identify potential vaccine components." "Open reading frames within immuno-reactive phage were analyzed in silica to identify conserved outer rnembrane proteins. Four ORFs, named comL, lolB, IppC and ompA were chosen for further study. The four encoded proteins were shown experimentally to be antigenic, highly conserved, outer membrane, in vivo-expressed proteins," wrote N.J. Oldfield and...
Source: Vaccine Weekly (2008-06-04)
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