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Rotavirus
New rotavirus study results from Baylor College of Medicine, College of Medicine described
June 4th, 2008
"Correlates of protection from rotavirus infection are controversial. We compared the roles of B and T lymphocytes in protective immunity induced either by intranasally administered nonreplicating viruslike particles or inactivated virus or by orally administered marine rotavirus," scientists writing in the Journal of Virology report. "We found that protection induced by nonreplicating vaccines requires CD4(+) T cells and CD40/CD40L. In contrast, T cells were not required for short-term protective immunity induced by infection, but both T-cell-dependent and -independent mechanisms contributed to long-term maintenance of protection," wrote S.E. Blutt and...
Source: Vaccine Weekly (2008-06-04)
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