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Foot and Mouth Disease



New data from V.L. Fowler et al illuminate research in foot and mouth disease



June 4th, 2008

"Previous work in pigs, has demonstrated that full protection against foot-and-mouth disease (FMD) can be achieved following vaccination with chimeric foot-and-mouth disease virus (FMDV) vaccines, in which the VP1 G-H loop had been substituted with that from another serotype. If proven to be effective in other economically important species such as cattle, such vaccine constructs could be trialed as potential marker vaccines," scientists in Woking, the United Kingdom report.

"Here, we determine if G-H loop chimera FMDV vaccines can: (i) protect cattle from virus challenge and (ii) induce an antibody response that would enable the identification of infection, regardless...


Source: Vaccine Weekly (2008-06-04)

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