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Vaccine Weekly

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Spectroscopy



Research conducted at University of Naples has updated our knowledge about spectroscopy



June 11th, 2008

According to a study from Naples, Italy, "Shigella flexneri is a Gram-negative bacterium responsible for serious enteric infections that occur mainly in the terminal ileum and colon. High interest in Shigella, as a human pathogen, is driven by its antibiotic resistance and the necessity to develop a vaccine against its infections."

"Vaccines of the last generation use carbohydrate moieties of the lipopolysaccharide as probable candidates. For this reason, the primary structure of the core oligosaccharide from the R-LPS produced by S. flexneri M90T serotype 5 using chemical analysis, nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MALDI), is herein...


Source: Vaccine Weekly (2008-06-11)

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