Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
DNA Vaccines
Data on DNA vaccines reported by researchers at Johns Hopkins Medical Institutions, Department of Pathology
June 11th, 2008
Fresh data on dna are presented in the report 'Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun.' "Administration of DNA vaccines via gene gun has emerged as an important form of Ag-specific immunotherapy. The MHC CIITA is a master regulator of MHC class II expression and also induces expression of class I molecules," researchers in the United States report. "We reasoned that the gene gun administration of CIITA DNA with DNA vaccines employing different strategies to improve MHC I and II processing could enhance DNA vaccine potency. We observed that DC-1 cells transfected with CIITA DNA lead to higher expression of...
Source: Vaccine Weekly (2008-06-11)
|
