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Malaria Vaccines
New findings from University of Edinburgh in the area of malaria vaccines described
June 11th, 2008
Research findings, 'CD4+T cells do not mediate within-host competition between genetically diverse malaria parasites,' are discussed in a new report. "Ecological interactions between microparasite populations in the same host are an important source of selection on pathogen traits such as virulence and drug resistance. In the rodent malaria model Plasmodium chabaudi in laboratory mice, parasites that are more virulent can competitively suppress less virulent parasites in mixed infections," investigators in Edinburgh, the United Kingdom report. "There is evidence that some of this suppression is due to immune-mediated apparent competition, where an immune response...
Source: Vaccine Weekly (2008-06-11)
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