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Immunotherapy
Data on immunotherapy detailed by researchers at Medical University of Warsaw
June 11th, 2008
According to a study from Warsaw, Poland, "Many studies have demnstrated that interleukin 15 (IL-15) is a cytokine with strong antitumor properties and have suggested its potential use in tumor immunotherapy. IL-15 exerts its effect on innate and acquired immunity with the most prominent action in NK cells and CD8+ memory T cells." "Therefore, many authors have proposed that IL-15 could be a good candidate for augmenting the efficacy of vaccination strategies. In our experiments, in a model of B78-H1 murine transplantable melanoma, tumor-bearing mice were treated with different cytokine-gene modified tumor cell vaccines (producing TNF-alpha, GM-CSF, IL-12 or...
Source: Vaccine Weekly (2008-06-11)
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