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Children's Hospital of Pittsburgh
New vaccine approach prevents/reverses diabetes in lab study at Children's Hospital of Pittsburgh
June 11th, 2008
Microspheres carrying targeted nucleic acid molecules fabricated in the laboratory have been shown to prevent and even reverse new-onset cases of type 1 diabetes in animal models. The results of these studies were reported by diabetes researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and Baxter Healthcare Corporation. In a research study at Children's Hospital, the scientists injected the microspheres under the skin near the pancreas of mice with autoimmune diabetes. The microspheres were then captured by white blood cells known as dendritic cells which released the nucleic acid molecules within the dendritic cells. The...
Source: Vaccine Weekly (2008-06-11)
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