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University of Alabama at Birmingham
HIV infection stems from few viruses
June 11th, 2008
A new study reveals the genetic identity of human immunodeficiency virus (HIV), the version responsible for sexual transmission, in unprecedented detail. The finding provides important clues in the ongoing search for an effective HIV/AIDS vaccine, said researchers at the University of Alabama at Birmingham (UAB). The UAB team found that among billions of HIV variants only a few lead to sexual transmission. Earlier studies have shown that a 'bottleneck' effect occurs where few versions of the virus lead to infection while many variants are present in the blood. The UAB study is the first to use genetic analysis and mathematical modeling to identify...
Source: Vaccine Weekly (2008-06-11)
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