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Vaccine Weekly

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Immunization



Data from D.G. Brooks et al provide new insights into immunization



June 18th, 2008

According to recent research from the United States, "Therapeutic vaccination is a potentially powerful strategy to establish immune control and eradicate persistent viral infections. Large and multifunctional antiviral T cell responses are associated with control of viral persistence; however, for reasons that were mostly unclear, current therapeutic vaccination approaches to restore T cell immunity and control viral infection have been ineffective."

"Herein, we confirmed that neutralization of the immunosuppressive factor interleukin (IL)-10 stimulated T cell responses and improved control of established persistent lymphocytic choriomeningitis virus (LCMV) infection....


Source: Vaccine Weekly (2008-06-18)

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