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Life Sciences
Investigators at China Agricultural University publish new data on life sciences
June 18th, 2008
According to recent research from Beijing, People's Republic of China, "The structure of the peptide-binding specificity of major histocompatibility complex (MHC) class I has been analyzed extensively in human and mouse. For fish, there are no crystallographic models of MHC molecules, neither are there data on the peptide-binding specificity." "In this study, we describe for the first time the identification of a fish class I peptide-MHC ligand binding motif. Phage display technology using both L 7 met and 12 mer libraries enabled us to identify peptide ligands with unique specificity that interacts with the recombinant Salmon MHC class I molecule. The recombinant...
Source: Vaccine Weekly (2008-06-18)
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