Cancer Gene Therapy

Researchers from Ajou University, Medical Department detail findings in cancer gene therapy

Published in Vaccine Weekly, June 18th, 2008

"Gastric cancer has the highest incidence rate among cancers in Asia. The advanced type of signet ring cell carcinoma has poor prognosis compared to other types of gastric cancer," researchers in South Korea report.

"The immuno-gene therapy with cytokine-based tumor vaccines has not yet been investigated for gastric cancer. The granulocyte macrophage colony-stimulating factor (GMCSF)-based tumor vaccine has been demonstrated as the most potent stimulator for specific and long-lasting systemic tumor immunity. In the present study, KATO III cells, the human signet ring cell gastric carcinoma cell line, were genetically modified by the transduction with the human GM-CSF...

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Source: Vaccine Weekly (2008-06-18)

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