Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Vaccines
Researchers from Emory University, Emory Vaccine Center detail new studies and findings in the area of vaccines
June 18th, 2008
"Little is known about herpesvirus modulation of T cell activation in latently infected individuals or the implications of such for chronic immune disorders. Murine gammaherpesvirus 68 (MHV68) elicits persistent activation of CD8(+) T cells bearing a V beta 4(+) T cell receptor (TCR) by a completely unknown mechanism," scientists in the United States report. "We show that a novel MHV68 protein encoded by the M1 gene is responsible for V beta 4(+) CD8(+) T cell stimulation in a manner reminiscent of a viral superantigen. During infection, M1 expression induces a V beta 4(+) effector T cell response that resists functional exhaustion and appears to suppress virus...
Source: Vaccine Weekly (2008-06-18)
|
