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Vaccine Weekly

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Vaccines



Research on vaccines published by D. Acosta et al



June 25th, 2008

According to recent research from Montevideo, Uruguay, "Leucyl aminopeptidases (LAP) from different parasitic organisms are attracting attention as relevant players in parasite biology, and consequently being considered as candidates for drug and vaccine design. In fact, the highest protection level achieved in ruminant immunization by a native antigen was previously reported by us, using a purified LAP as immunogen in a sheep trial against fasciolosis."

"Here, we report the cloning of a full-length cDNA from adult F hepatica encoding a member of the M 17 family of LAP (FhLAP) and functional expression and characterization of the corresponding enzyme. FhLAP was closely...


Source: Vaccine Weekly (2008-06-25)

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