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Vaccine Weekly

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Anthrax Vaccines



Findings from Centers for Disease Control and Prevention advance knowledge in anthrax vaccines



June 25th, 2008

Current study results from the report, 'Standardized, mathematical model-based and validated in vitro analysis of anthrax lethal toxin neutralization,' have been published. According to a study from the United States, "Quantification of anthrax lethal toxin (LTx) neutralization activity (TNA) is pivotal in assessing protective antibody responses to anthrax vaccines and for evaluation of immunotherapies for anthrax. We have adapted and redesigned the TNA assay to establish a unifying, standardized, quantitative and validated technology platform for LTx neutralization in the J774A.1 murine cell line."

"Critical design features of this platform are 1) the application of a...


Source: Vaccine Weekly (2008-06-25)

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