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Immunization
Reports summarize immunization study results from University Hospital
June 25th, 2008
Researchers detail in 'Canine MDCK cell lines are refractory to infection with human and mouse prions,' new data in immunization. "Influenza vaccine production in embryonated eggs is associated with many disadvantages, and production in cell culture systems is a viable alternative. Madin Darby canine kidney (MDCK) cells are permissive for a variety of orthomyxoviruses and have proven particularly suitable for vaccine mass production," scientists in Zurich, Switzerland report. "However, mammalian cells harboring the Prnp gene can theoretically acquire prion infections. Here, we have attempted to infect MDCK cells and substrains thereof with prions. We found that MDCK...
Source: Vaccine Weekly (2008-06-25)
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