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Tissue Engineering
New tissue engineering study findings recently were reported by researchers at Institute of Genetics
June 25th, 2008
Current study results from the report, 'Protection of IgE-mediated allergic sensitization by active immunization with IgE loops constrained in GFP protein scaffold,' have been published. According to recent research from the United States, "Green fluorescent protein (GFP) exhibits a rigid central beta-barrel, formed by eleven beta-strands with floppy loops spanning between the stands. Herein, we evaluate whether the rigid beta-barrel may serve as a scaffold that can constrain the loops of a foreign protein, and thus its antigenicity." "The spanning loops, site 6 of GFP, were engineered with RE cloning sites for inserting oligonucleotides corresponding to...
Source: Vaccine Weekly (2008-06-25)
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