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Foot and Mouth Disease



New foot and mouth disease research reported from Huazhong Agricultural University



June 25th, 2008

"Foot-and-mouth disease (FMD) is the most contagious and devastating disease of livestock. Our previous studies demonstrated that TK-/gG(-)/P1(+), a recombinant expressing the FMDV capsid precursor protein (P1) based on attenuated pseudorabies virus (PRV) TK-/gG(-), could be used as a recombinant vaccine to protect pigs against both pseudorabies and FMD," scientists in Wuhan, People's Republic of China report.

"However, because the P1 expression cassette is inserted into the gG locus of the genome of PRV TK-/gG(-), this bivalent vaccine cannot be used in conjunction with the PRV gE-ELISA, an extensively used discriminatory serological test in eradication programs for...


Source: Vaccine Weekly (2008-06-25)

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