Helicobacter pylori

Investigators at University of Michigan target helicobacter pylori

Published in Vaccine Weekly, June 25th, 2008

According to recent research from the United States, "The growing concern over the emergence of antibiotic-resistant Helicobacter pylori infection is propelling the development of an efficacious vaccine to control this highly adaptive organism. We studied the use of a dendritic cell (DC)-based vaccine against H. pylori infection in mice."

"The cellular immune responses to murine bone marrow-derived DCs pulsed with phosphate-buffered saline (PBS-DC) or live H. pylori SS1 (HP-DC) were assessed in vitro and in vivo. The protective immunity against H. pylori SS1 oral challenge was compared between HP-DC or PBS-DC immunized mice. The effect of regulatory T-cell (Treg)...

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Source: Vaccine Weekly (2008-06-25)

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