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Vaccine Weekly

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Helicobacter pylori



Investigators at University of Michigan target helicobacter pylori



June 25th, 2008

According to recent research from the United States, "The growing concern over the emergence of antibiotic-resistant Helicobacter pylori infection is propelling the development of an efficacious vaccine to control this highly adaptive organism. We studied the use of a dendritic cell (DC)-based vaccine against H. pylori infection in mice."

"The cellular immune responses to murine bone marrow-derived DCs pulsed with phosphate-buffered saline (PBS-DC) or live H. pylori SS1 (HP-DC) were assessed in vitro and in vivo. The protective immunity against H. pylori SS1 oral challenge was compared between HP-DC or PBS-DC immunized mice. The effect of regulatory T-cell (Treg)...


Source: Vaccine Weekly (2008-06-25)

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