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Vaccine Weekly

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Vaccines



Researchers from La Jolla Institute for Allergy and Immunology publish new studies and findings in the area of vaccines



July 2nd, 2008

New investigation results, 'Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities,' are detailed in a study published in Immunity. According to a study from the United States, "Antibody responses are critical components of protective immune responses to many pathogens, but parameters determining which proteins are targeted remain unclear. Vaccination with individual MHC-II-restricted vaccinia virus (VACV, smallpox vaccine) epitopes revealed that CD4(+) T cell help to B cells was surprisingly nontransferable to other virion protein specificities."

"Many VACV CD4(+) T cell responses identified in an...


Source: Vaccine Weekly (2008-07-02)

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