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Cancer Vaccines
Research from National Cancer Institute in the area of cancer vaccines described
July 2nd, 2008
"Assays to measure biomarkers are commonly subject to large amounts of measurement error and known detection limits. Studies with longitudinal biomarker measurements may use multiple assays in assessing outcome," scientists in the United States report. "I propose an approach for jointly modeling repeated measures of multiple assays when these assays are subject to measurement error and known lower detection limits. A commonly used approach is to perform an initial assay with a larger lower detection limit on all repeated samples, followed by only performing a second more expensive assay with a lower minimum level of detection when the initial assay value is below its...
Source: Vaccine Weekly (2008-07-02)
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