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DNA Vaccines
New DNA vaccines study findings have been published by scientists at Autonomous University
July 2nd, 2008
"Immunization of BALB/c mice with a DNA vaccine encoding the nucleosomal histones from Leishmania infantum resulted in a complete failure of protection against visceral leishmaniosis (VL), whereas the adoptive transfer of bone marrow-derived dendritic cells pulsed with the same pathoantigens plays an essential role in controlling parasite growth in half of the cases," scientists in Madrid, Spain report. "Reduction of the visceral parasite burden seems to be related to low persistence of regulatory T-cells in the spleen from vaccinated mice," wrote J. Carrion and colleagues, Autonomous University. The researchers concluded: "These results provide...
Source: Vaccine Weekly (2008-07-02)
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