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Vaccine Weekly

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Life Sciences



Studies in the area of life sciences reported from Department of Agriculture



July 2nd, 2008

According to recent research from the United States, "During development and subsequent field evaluation of an oral vaccinia-rabies glycoprotein (V-RG) recombinant virus vaccine, 53 adult porcupines (Erethizon dorsatum; 38 females and 15 males) were examined. Microscopic examinations revealed the presence of giant epitheloid cells in various tissues (adrenal glands, spleen, liver, and lungs) of 4 (11%) female animals."

"These giant cells were approximately 20 times the size of the surrounding cells of the parenchyma. The cells were found singly and were not associated with any inflammatory cellular infiltrate and appeared to be located within vascular lumina....


Source: Vaccine Weekly (2008-07-02)

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