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Vaccinia Virus

New vaccinia virus data have been reported by researchers at National Institute of Allergy and Infectious Disease

Published in Vaccine Weekly, July 2nd, 2008

A report, 'A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture,' is newly published data in Virology. According to a study from the United States, "Of the vaccinia virus genes that are conserved in all sequenced poxviruses, each one except for VACWR084 (G6R) has been at least partially characterized. The poxvirus protein encoded by G6R belongs to the NlpC/P60 superfamily, which consists of proteins with a papain-like fold and known or predicted protease, amidase or acyltransferase activity."

"The G6 protein was synthesized late in infection and localized to the interior of...

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