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Vaccine Weekly

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Asthma



Study results from R. Kuolee and colleagues in the area of asthma published



July 9th, 2008

According to recent research from Ottawa, Canada, " It has been suggested that exposure to certain microbes and their products, particularly during neonatal and early childhood periods, may shift the immune response towards a T-helper cell (Th) 1 phenotype and thereby prevent the development of and/or alleviate the clinical symptoms of allergic airway diseases. We evaluated the ability of the live vaccine strain (LVS) of Francisella tularensis to suppress airway eosinophilia and pulmonary pathology in a murine model of allergic airway disease."

" C57BL/6 mice were sensitized by intraperitoneal injection of ovalbumin (OVA) on days 1 and 14, and challenged intranasally...


Source: Vaccine Weekly (2008-07-09)

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