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Vaccine Weekly

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Immunotherapy



Research on immunotherapy reported by scientists at University of Freiburg, Department of Hematology-Oncology



July 9th, 2008

Current study results from the report, 'Dendritic cell maturation with poly(I:C)-based versus PGE2-based cytokine combinations results in differential functional characteristics relevant to clinical application,' have been published. According to recent research published in the Journal of Immunotherapy, "In vitro maturation of dendritic cells (DCs) for cancer immunotherapy may be accomplished by cytokine cocktails containing prostaglandin E2 (PGE2). More recently, a poly(I:C)-based protocol has been proposed as a potentially superior alternative because of a strong induction of interleukin (IL)-12 secretion by resulting DCs."

"As optimal DC maturation represents...


Source: Vaccine Weekly (2008-07-09)

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