Yellow Fever Vaccines

Reports from L.P. Gaspar and co-researchers add new data to research in yellow fever vaccines

Published in Vaccine Weekly, July 9th, 2008

A new study, 'Pressure-inactivated yellow fever 17DD virus: implications for vaccine development,' is now available. "The successful Yellow Fever (YF) vaccine consists of the live attenuated 17D-204 or 17DD viruses. Despite its excellent record of efficacy and safety, serious adverse events have been recorded and influenced extensive vaccination in endemic areas," scientists in Rio de Janeiro, Brazil report.

"Therefore, alternative strategies should be considered, which may include inactivated whole virus. High hydrostatic pressure has been described as a method for viral inactivation and vaccine development. The present study evaluated whether high hydrostatic pressure...

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Source: Vaccine Weekly (2008-07-09)

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