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Vaccine Weekly

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Immunization



Researchers from University Hospital describe findings in immunization



July 9th, 2008

In this recent study, researchers in Louvain, Belgium conducted a study "To investigate the therapeutic role of adjuvant vaccination with autologous mature dendritic cells (DC) loaded with tumor lysates derived from autologous, resected glioblastoma multiforme (GBM) at time of relapse. Fifty-six patients with relapsed GBM (WHO grade IV) were treated with at least three vaccinations."

"Children and adults were treated similarly in three consecutive cohorts, with progressively shorter vaccination intervals per cohort. Feasibility and toxicity were assessed as well as effect of age, extent of resection, Karnofsky Performance Score, and treatment cohort on the...


Source: Vaccine Weekly (2008-07-09)

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