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Vaccine Weekly

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Cytomegalovirus



Scientists at University of California describe research in cytomegalovirus



July 16th, 2008

"A vaccine consisting of rhesus cytomegalovirus (RhCMV) pp65-2, gB and IE1 expressed via modified vaccinia Ankara (MVA) was evaluated in rhesus macaques with or without prior priming with expression plasmids for the same antigens," researchers in the United States report.

"Following two MVA treatments, comparable levels of anti-gB, pp65-2 and neutralizing antibody responses, and pp65-2- and IE1-specific cellular immune responses were detected in both vaccinated groups. Similar reductions in plasma peak viral loads were observed in these groups compared to untreated controls," wrote Y.J. Yue and colleagues, University of California.

The researchers...


Source: Vaccine Weekly (2008-07-16)

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