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Vaccine Weekly

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Vaccines



Study findings from F.R. Araujo et al provide new insights into vaccines



July 16th, 2008

According to a study from Campo Grande, Brazil, "Anaplasma marginale is an important vector-borne rickettsia of ruminants in tropical and subtropical regions of the world. Immunization with purified outer membranes of this organism induces protection against acute anaplasmosis."

"Previous studies, with proteomic and genomic approach identified 21 proteins within the outer membrane immunogen in addition to previously characterized major surface protein1a-5 (MSP1a-5). Among the newly described proteins were VirB9, VirB10, and elongation factor-Tu (EF-Tu). VirB9, VirB10 are considered part of the type IV secretion system (TFSS), which mediates secretion or cell-to-cell...


Source: Vaccine Weekly (2008-07-16)

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