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Life Sciences
Studies from University Hospital have provided new data on life sciences
July 16th, 2008
Current study results from the report, 'CD47 expression on T cell is a self-control negative regulator of type 1 immune response,' have been published. "The cytokine milieu and dendritic cells (DCs) direct Th1 development. Yet, the control of Th1 polarization by T cell surface molecules remains ill-defined," scientists writing in the Journal of Immunology report. "We here report that CD47 expression on T cells serves as a self-control mechanism to negatively regulate type 1 cellular and humoral immune responses in vivo. Th2-prone BALB/c mice that lack CD47 (CD47(-/-)) displayed a Th1-biased Ab profile at steady state and after immunization with soluble Ag....
Source: Vaccine Weekly (2008-07-16)
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