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Monoclonal Antibodies
Data on monoclonal antibodies described by researchers at National Institutes of Health
July 16th, 2008
Investigators publish new data in the report 'Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects.' "Radiolabeled monoclonal antibodies (mAb) have demonstrated measurable antitumor effects in hematologic malignancies. This outcome has been more difficult to achieve for solid tumors due, for the most part, to difficulties in delivering sufficient quantities of mAb to the tumor mass," scientists in the United States report. "Previous studies have shown that nonlytic levels of external beam radiation can render tumor cells more susceptible to T cell-mediated killing. The goal of these studies was to determine if the selective delivery of a...
Source: Vaccine Weekly (2008-07-16)
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