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Encephalomyelitis
Research from Fourth Military Medical University, Medical University Center in the area of encephalomyelitis published
July 23rd, 2008
According to recent research from Xian, People's Republic of China, "The B-lymphocyte stimulator (BLyS) is implicated in various pathophysiological processes. The overexpression of BLyS has been observed in some human diseases, including systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome, and multiple sclerosis." "This feature suggests that BLyS may be a therapeutic target for some human autoimmune diseases. We developed a therapeutic vaccine by coupling a tetanus toxoid T-helper cell epitope with the C-terminal of BLyS (TT-BLyS). This vaccine can induce high titers of neutralizing antibodies against BLyS in an animal model; the antibody has markedly...
Source: Vaccine Weekly (2008-07-23)
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