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Vaccine Weekly

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Escherichia coli



Studies in the area of Escherichia coli reported from S.A. Frech and co-researchers



July 23rd, 2008

According to recent research from the United States, " Enterotoxigenic Escherichia coli (ETEC) is a major cause of travellers' diarrhoea. We investigated the rate of diarrhoea attacks, safety, and feasibility of a vaccine containing heat-labile enterotoxin (LT) from ETEC delivered to the skin by patch in travellers to Mexico and Guatemala."

" In this phase 11 study, healthy adults (aged 18-64 years) who planned to travel to Mexico or Guatemala and had access to a US regional vaccination centre were eligible. A centralised randomisation code was used for allocation, which was masked to participants and site staff. Primary endpoints were to investigate the field rate of...


Source: Vaccine Weekly (2008-07-23)

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