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Vaccine Weekly

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Immunization



New findings reported from University of Ottawa describe advances in immunization



July 23rd, 2008

According to a study from Ottawa, Canada, "To stimulate the immune system's natural defenses, a post-infection HIV vaccination program to regularly boost cytotoxic T-lymphocytes has been proposed. We develop a mathematical model to describe such a vaccination program, where the strength of the vaccine and the vaccination intervals are constant."

"We apply the theory of impulsive differential equations to show that the model has an orbitally asymptotically stable periodic orbit, with the property of asymptotic phase. We show that, on this orbit, the vaccination frequency can be chosen so that the average number of infected CD4(+) T cells can be made arbitrarily low,"...


Source: Vaccine Weekly (2008-07-23)

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