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Immunization
Data on immunization published by researchers at Technical University of Munich, Institute for Medical Microbiology
July 23rd, 2008
Data detailed in 'Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity' have been presented. According to recent research published in the European Journal of Immunology, "Immunization with purified antigens is a safe and practical vaccination strategy but is generally unable to induce sustained CD8(+) T cell-mediated protection against intracellular pathogens. Most efforts to improve the CD8(+) T cell immunogenicity of these vaccines have focused on co-administration of adjuvant to support cross-presentation and dendritic cell maturation." "In addition, it has been shown that CD4(+) T cell help during...
Source: Vaccine Weekly (2008-07-23)
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