Immunization
Study findings from Institute for Neurobiology provide new insights into immunization
Published in Vaccine Weekly, July 23rd, 2008
New research, 'DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis,' is the subject of a report. "Antibodies against the neurite outgrowth inhibitor Nogo-A enhance axonal regeneration following spinal cord injury. However, antibodies directed against myelin components can also enhance CNS inflammation," scientists writing in the European Journal of Pharmacology report.
"The present study was designed to assess the efficacy of DNA vaccination for generating antibodies against Nogo-A and to study their pathogenic potential in a mouse model for multiple sclerosis. Mice were immunized by a single...
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Source: Vaccine Weekly (2008-07-23)
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