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Severe Acute Respiratory Syndrome Vaccines



Research from Seoul National University provides new data about severe acute respiratory syndrome vaccines



July 23rd, 2008

A new study, 'Search for potential target site of nucleocapsid gene for the design of an epitope-based SARS DNA vaccine,' is now available. According to a study from Seoul, Korea, "It is believed today that nucleocapsid protein (N) of severe acute respiratory syndrome (SARS)-CoV is one of the most promising antigen candidates for vaccine design. In this study, three fragments [N1 (residues: 1-422); N2 (residues: 1-109); N3 (residues: 110-422)] of N protein of SARS-CoV were expressed in Escherichia coli and analyzed by pooled sera of convalescence phase of SARS patients."

"Three gene fragments [N1 (1-1269 nt), N2 (1-327 nt) and N3 (328-1269 nt)-expressing the same...


Source: Vaccine Weekly (2008-07-23)

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