Antibody Libraries

New research on antibody libraries from A.K. Kashyap and co-authors summarized

Published in Vaccine Weekly, July 23rd, 2008

"The widespread incidence of H5N1 influenza viruses in bird populations poses risks to human health. Although the virus has not yet adapted for facile transmission between humans, it can cause severe disease and often death," researchers in the United States report.

"Here we report the generation of combinatorial antibody libraries from the bone marrow of five survivors of the recent HSN1 avian influenza outbreak in Turkey. To date, these libraries have yielded >300 unique antibodies against H5N1 viral antigens. Among these antibodies, we have identified several broadly reactive neutralizing antibodies that could be used for passive immunization against H5N1 virus or...

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Source: Vaccine Weekly (2008-07-23)

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