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Vaccine Weekly

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Life Sciences



Research from J.K. Whitmire and co-researchers provides new data on life sciences



July 30th, 2008

According to recent research from the United States, "T cell memory is a cornerstone of protective immunity, and is the key element in successful vaccination. Upon encountering the relevant pathogen, memory T cells are thought to initiate cell division much more rapidly than their naive counterparts, and this is thought to confer a significant biological advantage upon an immune host."

"Here, we use traceable TCR-transgenic T cells to evaluate this proposed characteristic in CD4(+) and CD8(+) memory T cells. We find that, even in the presence of abundant antigen that was sufficient to induce in vivo IFN gamma production by memory T cells, both memory and naive T cells...


Source: Vaccine Weekly (2008-07-30)

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