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Vaccines
New vaccines data have been reported by researchers at University of Pecs
July 30th, 2008
According to recent research from Pecs, Hungary, "Lipopolysaccharide (LIPS) is an essential component of Gram-negative bacteria. While mutants exhibiting truncated LPS molecules are usually over-attenuated, alternative approaches that affect the extent or timing of LPS expression, as well as its modification may establish the optimal balance for a live vaccine strain of sufficient attenuation and retained immunogenicity." "On the other hand, a specific immune response to LIPS molecules in itself is capable of conferring protective immunity to certain enterobacterial pathogens. Therefore, purified LIPS derivatives could be used as parenteral vaccines," wrote G. Nagy and...
Source: Vaccine Weekly (2008-07-30)
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