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Immunization
Data on immunization reported by B. Valentinis and co-researchers
July 30th, 2008
New research, 'Human recombinant heat shock protein 70 affects the maturation pathways of dendritic cells in vitro and has an in vivo adjuvant activity,' is the subject of a report. According to recent research published in the Journal of Leukocyte Biology, "Heat shock proteins (HSPs) are potent inducers of an antigen-specific immunological response. A role of chaperon of immunogenic peptides and a direct effect on APC activation and function have been described." "However, the signal transduction events involved in the activation of human APCs are poorly characterized. We investigated, using human monocyte-derived dendritic cells (DCs), the signal transduction...
Source: Vaccine Weekly (2008-07-30)
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