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Vaccine Weekly

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HIV/AIDS



New research on HIV/AIDS from N. Teleshova and co-authors summarized



July 30th, 2008

According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "Without an effective vaccine against human immunodeficiency virus (HIV) infection, topical microbicide development has become a priority. The sulfonated polyanion PRO 2000, a candidate topical microbicide now in phase II/III clinical trials, blocks HIV infection of cervical tissue in vitro."

"Dendritic cells (DC) are among the first cell types to contact HIV in the genital tract and facilitate the spread of the virus. Thus, interfering with virus-DC interactions is a desirable characteristic of topical microbicides as long as that does not interfere with the normal...


Source: Vaccine Weekly (2008-07-30)

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