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Vaccine Weekly

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Immunotherapy



Data on immunotherapy reported by G.F. Kaufmann and co-researchers



July 30th, 2008

"Cell-to-cell communication via exchange of small molecules, 'autoinducers', is a widespread phenomenon among Gram-negative and -positive bacteria. This intercellular signaling that synchronizes population-wide gene expression in a cell-density-dependent manner is termed 'quorum sensing' (QS)," scientists writing in the journal Expert Opinion on Biological Therapy report.

"The discovery that Gram-negative bacteria employ non-peptide structures, N-acyl homoserine lactones, to globally regulate production of secondary metabolites and proteins, initiated a new area of research. Subsequently, other quorum-sensing systems and small signaling molecules were identified....


Source: Vaccine Weekly (2008-07-30)

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